Buck Institute Research

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Date/Time
Date(s) - Wednesday, October 7, 2015
12:00 am

Location
Flamingo Conference Resort and Spa

Buck Institute Research

The Buck Institute is the nation’s first independent research facility focused solely on understanding the connection between aging and chronic disease. Their mission is to increase the healthy years of life. The Institute is designed for the free flow of information. Discoveries quickly result in new studies.

At the Buck Institute, world-class scientists work collaboratively to understand how normal aging contributes to the development of conditions specifically associated with getting older such as Alzheimer’s and Parkinson’s diseases, cancer, stroke, osteoporosis, heart disease, diabetes, macular degeneration and glaucoma. Our interdisciplinary approach brings scientists from disparate fields together to develop diagnostic tests and treatments to prevent or delay these maladies.

Dr. Mangada earned her Ph.D. in Molecular Medicine from the University of Massachusetts Medical School in 2007 specializing in immunology Dr. Mangada joined the Buck Institute for Research on Aging in 2008. Dr. Mangada couples her background in immunology with her contemporary embryonic stem cell experience to investigate stem cell epigenetics and how genetic erosion and DNA repair mechanisms contribute with cell replacement therapies. Dr. Mangada recently accepted a position at the Institute as a full-time K-12 outreach.

Julie Mangada, PhD Molecular Medicine

Raised in Petaluma CA, Dr. Mangada began her education at SRJC in Santa Rosa and went on to earn her B.S. in Microbiology from the University of New Hampshire in 2000. She earned her Ph.D. in Molecular Medicine from the University of Massachusetts Medical School in 2007. Specializing in immunology, her doctoral research worked to tease apart the molecular mechanisms of autoimmunity and how they relate to transplantation tolerance induction. Dr. Mangada joined the Buck Institute for Research on Aging in 2008 as a Post Doctoral researcher in the laboratory of Xianmin Zeng, Ph.D. In a departure from her doctoral studies she began working with human embryonic stem cells (hESC) and their directed differentiation into neurons for cell replacement therapies. Dr. Mangada’s studies led to the development of an in vivo non-invasive MRI-based imaging platform for studying transplanted dopaminergic neurons during the peri-transplant period in a Parkinson’s Disease model. She expanded the breadth and scope of her inquiries at the Buck Institute by joining the laboratory of Judith Campisi, Ph.D. in 2010. In the Campisi laboratory Dr. Mangada couples her background in immunology with her contemporary embryonic stem cell experience to investigate stem cell epigenetics and how genetic erosion and DNA repair mechanisms contribute to the suitability of hESC in cell replacement therapies. In addition to her research, Dr. Mangada dedicated 20% of her effort at the Institute to educational outreach. Whether science is polarizing theological beliefs, promising to cure devastating diseases or prompting individuals to ask pertinent questions about the future of our aging population or environment Dr. Mangada believes it is the golden thread that weaves together all the diverse fabrics of our society. Her philosophy is that science should be accessible to everybody because it permeates all aspects of our culture, leading her to be a huge advocate of early science education. During her short tenure as the Education Outreach Coordinator at the Buck Institute, Dr. Mangada’s efforts have lead to the creation of several dynamic new community outreach programs, some of which include a weekend Science Boot Camp, a summer Algebra Academy, elementary school molecular biology classes and a high school lecture series designed to bring Buck Institute research to local students. She works with both Sonoma and Marin Counties’ Directors for the Program in Biotechnology Education (PROBE), the Sonoma County Gifted and Talented Education (GATE) program and sits on the Board of the Sonoma County Office of Education Biotechnology Advisory Committee and the Novato Unified School District’s STEM Program Steering Committee. With a staff of volunteers, she brought the UCSF Science Festival north of the Golden Gate Bridge and every October hosts the North Bay Science Discovery Day at the Santa Rosa Fairgrounds; an event that draws 15,000 people to an exciting hands-on experience designed to showcase the science going on in our own communities. Dr. Mangada recently accepted a position at the Institute as a full-time K-12 outreach coordinator because she believes that everybody has a vested interest, whether as individuals or as a society, in scientific literacy.

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